Les effets de la restriction calorique

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Réféfences

1. Comparative Effects of Caloric Restriction and Total Starvation on Body Composition in Obesity. Annals of Internal Medicine, 1967. 67(1): p. 60–67.
2. Adeva-Andany, M.M., et al., Glycogen metabolism in humans. BBA Clinical, 2016. 5: p. 85–100.
3. Amaro-Gahete, F.J., et al., Congruent Validity of Resting Energy Expenditure Predictive Equations in Young Adults. Nutrients, 2019. 11(2): p. 223.
4. Amati, F., et al., Separate and combined effects of exercise training and weight loss on exercise efficiency and substrate oxidation. Journal of applied physiology (1985), 2008. 105(3): p. 825–831.
5. Ashtary-Larky, D., et al., Effects of gradual weight loss vs. rapid weight loss on body composition and RMR: a systematic review and meta-analysis. British Journal of Nutrition, 2020. 124(11): p. 1121–1132.
6. BALL, M.F., L.H. KYLE, and J.J. CANARY, Comparative effects of caloric restriction and metabolic acceleration on body composition in obesity. The Journal of Clinical Endocrinology & Metabolism, 1967. 27(2): p. 273–278.
7. Batorek, M. and I. Hromatko, Cognitive Functions, Mood and Sleep Quality after Two Months of Intermittent Fasting. Journal of Trial and Error, 2024.
8. Begaye, B., et al., Impaired Metabolic Flexibility to High-Fat Overfeeding Predicts Future Weight Gain in Healthy Adults. Diabetes, 2020. 69(2): p. 181–192.
9. Benedict, F.G., The Influence of Inanition on Metabolism. 1907: Carnegie Institution of Washington.
10. Benedict, F.G., et al., A Study of Prolonged Fasting. 1915: Carnegie Institution of Washington.
11. Benedict, F.G., et al., Human Vitality and Efficiency Under Prolonged Restricted Diet. 1919: Carnegie Institution pf Washington. 701.
12. Bosy-Westphal, A., et al., Issues in characterizing resting energy expenditure in obesity and after weight loss. Frontiers in Physiology, 2013. 4.
13. Bosy-Westphal, A., et al., Deep body composition phenotyping during weight cycling: relevance to metabolic efficiency and metabolic risk. Obesity Reviews, 2015. 16(S1): p. 36–44.
14. Bosy-Westphal, A., et al., Contribution of individual organ mass loss to weight loss–associated decline in resting energy expenditure2. The American Journal of Clinical Nutrition, 2009. 90(4): p. 993–1001.
15. Bosy-Westphal, A., et al., Effect of weight loss and regain on adipose tissue distribution, composition of lean mass and resting energy expenditure in young overweight and obese adults. International Journal of Obesity, 2013. 37(10): p. 1371–1377.
16. Calonne, J., et al., Reduced Skeletal Muscle Protein Turnover and Thyroid Hormone Metabolism in Adaptive Thermogenesis That Facilitates Body Fat Recovery During Weight Regain. Frontiers in Endocrinology, 2019. 10.
17. Caristia, S., et al. Is Caloric Restriction Associated with Better Healthy Aging Outcomes? A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients, 2020. 12, DOI: 10.3390/nu12082290.
18. Caristia, S., et al., Is Caloric Restriction Associated with Better Healthy Aging Outcomes? A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients, 2020. 12(8): p. 2290.
19. Celi, F.S., T.N. Le, and B. Ni, Physiology and relevance of human adaptive thermogenesis response. Trends in Endocrinology & Metabolism, 2015. 26(5): p. 238–247.
20. Collet, T.-H., et al., A Metabolomic Signature of Acute Caloric Restriction. The Journal of Clinical Endocrinology & Metabolism, 2017. 102(12): p. 4486–4495.
21. Dahle, J.H., et al., Weight and body composition changes affect resting energy expenditure predictive equations during a 12-month weight-loss intervention. Obesity (Silver Spring), 2021. 29(10): p. 1596–1605.
22. Das, S.K., et al., Body-composition changes in the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE)-2 study: a 2-y randomized controlled trial of calorie restriction in nonobese humans1, 2, 3. The American Journal of Clinical Nutrition, 2017. 105(4): p. 913–927.
23. de Jonge, L., et al., Effect of diet composition and weight loss on resting energy expenditure in the POUNDS LOST study. Obesity (Silver Spring), 2012. 20(12): p. 2384–9.
24. de Jonge, L., et al., Validation study of energy expenditure and intake during calorie restriction using doubly labeled water and changes in body composition2. The American Journal of Clinical Nutrition, 2007. 85(1): p. 73–79.
25. De Lima Macena, M., et al., Longitudinal estimates of resting energy expenditure using predictive equations in individuals with excess weight after weight loss: A systematic review with meta-analysis. Clinical Nutrition ESPEN, 2023. 58: p. 263–269.
26. Deuel, H.J., et al., THE SEXUAL VARIATION IN CARBOHYDRATE METABOLISM: IX. THE EFFECT OF AGE ON THE SEX DIFFERENCE IN THE CONTENT OF LIVER GLYCOGEN. Journal of Biological Chemistry, 1937. 119(2): p. 617–620.
27. Di Munno, C., et al., Adaptive Thermogenesis Driving Catch-Up Fat Is Associated With Increased Muscle Type 3 and Decreased Hepatic Type 1 Iodothyronine Deiodinase Activities: A Functional and Proteomic Study. Frontiers in Endocrinology, 2021. 12.
28. Dorling, J.L., et al., Effects of caloric restriction on human physiological, psychological, and behavioral outcomes: highlights from CALERIE phase 2. Nutrition Reviews, 2021. 79(1): p. 98–113.
29. Dünnwald, T., et al., Body Composition and Body Weight Changes at Different Altitude Levels: A Systematic Review and Meta-Analysis. Frontiers in Physiology, 2019. 10.
30. Egan, A.M. and A.L. Collins, Dynamic changes in energy expenditure in response to underfeeding: a review. Proceedings of the Nutrition Society, 2022. 81(2): p. 199–212.
31. Farooqui, A.A., Effect of Long Term Consumption of High Calorie Diet and Calorie Restriction on Human Health. 2015, Springer International Publishing AG: Switzerland. p. 1–28.
32. Farooqui, A.A., High calorie diet and the human brain. 2015: Springer.
33. Fothergill, E., et al., Persistent metabolic adaptation 6 years after “The Biggest Loser” competition. Obesity, 2016. 24(8): p. 1612–1619.
34. Friedl, K.E., et al., Endocrine markers of semistarvation in healthy lean men in a multistressor environment. Journal of Applied Physiology, 2000. 88(5): p. 1820–1830.
35. Galgani, J.E. and J.L. Santos, Insights about weight loss‐induced metabolic adaptation. Obesity, 2016. 24(2): p. 277–278.
36. Gu, L., et al., Effects of intermittent fasting in human compared to a non-intervention diet and caloric restriction: a meta-analysis of randomized controlled trials. Frontiers in nutrition, 2022. 9: p. 871682.
37. Hall, K.D., The complicated relation between resting energy expenditure and maintenance of lost weight. Am J Clin Nutr, 2018. 108(4): p. 652–653.
38. Hamrick, M.W., et al., Caloric Restriction Decreases Cortical Bone Mass but Spares Trabecular Bone in the Mouse Skeleton: Implications for the Regulation of Bone Mass by Body Weight*. Journal of Bone and Mineral Research, 2009. 23(6): p. 870–878.
39. Handa, T., et al., Resting energy expenditure depends on energy intake during weight loss in people with obesity: a retrospective cohort study. Archives of Endocrinology and Metabolism, 2022.
40. Heinitz, S., et al., Early adaptive thermogenesis is a determinant of weight loss after six weeks of caloric restriction in overweight subjects. Metabolism, 2020. 110: p. 154303.
41. Heymsfield, S.B., et al., Why do obese patients not lose more weight when treated with low-calorie diets? A mechanistic perspective. Am J Clin Nutr, 2007. 85(2): p. 346–54.
42. Heymsfield, S.B., et al., Voluntary weight loss: systematic review of early phase body composition changes. Obesity Reviews, 2011. 12(5): p. e348–e361.
43. Hołowko, J., et al., Six Weeks of Calorie Restriction Improves Body Composition and Lipid Profile in Obese and Overweight Former Athletes. Nutrients, 2019. 11(7): p. 1461.
44. Ivy, J.L., Role of carbohydrate in physical activity. Clin Sports Med, 1999. 18(3): p. 469–84, v.
45. Kautzky, A., et al., Short Term Caloric Restriction and Biofeedback Enhance Psychological Wellbeing and Reduce Overweight in Healthy Women. Journal of Personalized Medicine, 2021. 11(11): p. 1096.
46. Keys, A., et al., The Biology of Human Starvation Volume I. 1950: University of Minnesota Press.
47. Keys, A., et al., The Biology of Human Starvation Volume II. NED – New edition ed. 1950: University of Minnesota Press.
48. Koubova, J. and L. Guarente, How does calorie restriction work? Genes & Development, 2003. 17(3): p. 313–321.
49. Krajmalnik‐Brown, R., et al., Effects of Gut Microbes on Nutrient Absorption and Energy Regulation. Nutrition in Clinical Practice, 2012. 27(2): p. 201–214.
50. Kreitzman, S.N., A.Y. Coxon, and K.F. Szaz, Glycogen storage: illusions of easy weight loss, excessive weight regain, and distortions in estimates of body composition. The American Journal of Clinical Nutrition, 1992. 56(1): p. 292S–293S.
51. Kruizenga, H.M., G.H. Hofsteenge, and P.J.M. Weijs, Predicting resting energy expenditure in underweight, normal weight, overweight, and obese adult hospital patients. Nutrition & Metabolism, 2016. 13(1): p. 85.
52. Krzywicki, H.J., et al., Metabolic aspects of caloric restriction (420 kcal) : body composition changes. The American Journal of Clinical Nutrition, 1972. 25(1): p. 67–73.
53. Luke, A., et al., Positive association between resting energy expenditure and weight gain in a lean adult population2. The American Journal of Clinical Nutrition, 2006. 83(5): p. 1076–1081.
54. MacLean, P.S., et al., Biology’s response to dieting: the impetus for weight regain. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2011. 301(3): p. R581–R600.
55. Major, G.C., et al., Clinical significance of adaptive thermogenesis. Int J Obes (Lond), 2007. 31(2): p. 204–12.
56. Marra, M., et al., Prediction and evaluation of resting energy expenditure in a large group of obese outpatients. International Journal of Obesity, 2017. 41(5): p. 697–705.
57. Martens, E.A., et al., Maintenance of energy expenditure on high-protein vs. high-carbohydrate diets at a constant body weight may prevent a positive energy balance. Clinical nutrition (Edinburgh, Scotland), 2015. 34(5): p. 968–975.
58. Mattson, M.P. and R. de Cabo, Effects of Intermittent Fasting on Health, Aging, and Disease. Reply. The New England journal of medicine, 2020. 382(18): p. 1773–1774.
59. McCue, M.D., Comparative physiology of fasting, starvation, and food limitation. 2012: Springer.
60. Mehta, T., et al., Impact of weight cycling on risk of morbidity and mortality. Obesity Reviews, 2014. 15(11): p. 870–881.
61. Miller, S., B.-J. Milliron, and K. Woolf, Common Prediction Equations Overestimate Measured Resting Metabolic Rate in Young Hispanic Women. Topics in Clinical Nutrition, 2013. 28(2): p. 120–135.
62. Most, J. and L.M. Redman, Impact of calorie restriction on energy metabolism in humans. Exp Gerontol, 2020. 133: p. 110875.
63. Most, J., et al., Calorie restriction in humans: An update. Ageing Research Reviews, 2017. 39: p. 36–45.
64. Müller, M.J. and A. Bosy-Westphal, Adaptive thermogenesis with weight loss in humans. Obesity, 2013. 21(2): p. 218–228.
65. Müller, M.J. and A. Bosy-Westphal, Effect of Over- and Underfeeding on Body Composition and Related Metabolic Functions in Humans. Current Diabetes Reports, 2019. 19(11).
66. Müller, M.J., J. Enderle, and A. Bosy-Westphal, Changes in Energy Expenditure with Weight Gain and Weight Loss in Humans. Curr Obes Rep, 2016. 5(4): p. 413–423.
67. Müller, M.J., et al., Metabolic adaptation to caloric restriction and subsequent refeeding: the Minnesota Starvation Experiment revisited. The American Journal of Clinical Nutrition, 2015. 102(4): p. 807–819.
68. Nunes, C.L., et al., Does adaptive thermogenesis occur after weight loss in adults? A systematic review. British Journal of Nutrition, 2022. 127(3): p. 451–469.
69. Nunes, C.L., et al., Adaptive thermogenesis after moderate weight loss: magnitude and methodological issues. European Journal of Nutrition, 2022. 61(3): p. 1405–1416.
70. O’Leary, J., C. Georgeaux-Healy, and L. Serpell, The impact of continuous calorie restriction and fasting on cognition in adults without eating disorders. Nutrition Reviews, 2025. 83(1): p. 146–159.
71. Ørtenblad, N., H. Westerblad, and J. Nielsen, Muscle glycogen stores and fatigue. The Journal of Physiology, 2013. 591(18): p. 4405–4413.
72. Ostendorf, D.M., et al., Physical Activity Energy Expenditure and Total Daily Energy Expenditure in Successful Weight Loss Maintainers. Obesity, 2019. 27(3): p. 496–504.
73. Piaggi, P., Metabolic Determinants of Weight Gain in Humans. Obesity (Silver Spring), 2019. 27(5): p. 691–699.
74. Piaggi, P., et al., Lower energy expenditure predicts long-term increases in weight and fat mass. J Clin Endocrinol Metab, 2013. 98(4): p. E703–7.
75. Pourhassan, M., et al., Impact of body composition during weight change on resting energy expenditure and homeostasis model assessment index in overweight nonsmoking adults1234. The American Journal of Clinical Nutrition, 2014. 99(4): p. 779–791.
76. Racette, S.B., et al., One Year of Caloric Restriction in Humans: Feasibility and Effects on Body Composition and Abdominal Adipose Tissue. The Journals of Gerontology: Series A, 2006. 61(9): p. 943–950.
77. Ravussin, E., S.R. Smith, and A.W. Ferrante Jr, Physiology of Energy Expenditure in the Weight-Reduced State. Obesity, 2021. 29(S1): p. S31–S38.
78. Redman, L.M., et al., Effect of Calorie Restriction with or without Exercise on Body Composition and Fat Distribution. The Journal of Clinical Endocrinology & Metabolism, 2007. 92(3): p. 865–872.
79. Redman, L.M., et al., Metabolic and Behavioral Compensations in Response to Caloric Restriction: Implications for the Maintenance of Weight Loss. PLoS ONE, 2009. 4(2): p. e4377.
80. Redman, L.M. and E. Ravussin, Endocrine alterations in response to calorie restriction in humans. Molecular and Cellular Endocrinology, 2009. 299(1): p. 129–136.
81. Redman, L.M. and E. Ravussin, Caloric Restriction in Humans: Impact on Physiological, Psychological, and Behavioral Outcomes. Antioxidants & Redox Signaling, 2011. 14(2): p. 275–287.
82. Rosenbaum, M., et al., Long-term persistence of adaptive thermogenesis in subjects who have maintained a reduced body weight1. The American Journal of Clinical Nutrition, 2008. 88(4): p. 906–912.
83. Rosenbaum, M. and R.L. Leibel, Adaptive thermogenesis in humans. Int J Obes (Lond), 2010. 34 Suppl 1(0 1): p. S47–55.
84. Rosenbaum, M. and R.L. Leibel, Adaptive thermogenesis in humans. International Journal of Obesity, 2010. 34(S1): p. S47–S55.
85. Ryan, A.S., H.K. Ortmeyer, and J.D. Sorkin, Exercise with calorie restriction improves insulin sensitivity and glycogen synthase activity in obese postmenopausal women with impaired glucose tolerance. American Journal of Physiology-Endocrinology and Metabolism, 2012. 302(1): p. E145–E152.
86. Salacinski, A.J., S.M. Howell, and D.L. Hill, Validity of the InBody 520™ to predict metabolic rate in apparently healthy adults. The Journal of sports medicine and physical fitness, 2018. 58(9): p. 1275–1280.
87. Sanaya, N., et al., The Physiological Effects of Weight-Cycling: A Review of Current Evidence. Current obesity reports, 2024. 13(1): p. 35–50.
88. Schleim, S., Cognitive or Emotional Improvement through Intermittent Fasting? Reflections on Hype and Reality. Journal of Trial and Error, 2024.
89. Schrauwen, P., et al., Fat balance in obese subjects: role of glycogen stores. American Journal of Physiology-Endocrinology and Metabolism, 1998. 274(6): p. E1027–E1033.
90. Schwartz, A. and E. Doucet, Relative changes in resting energy expenditure during weight loss: a systematic review. Obes Rev, 2010. 11(7): p. 531–47.
91. Schwartz, A., et al., Greater Than Predicted Decrease in Resting Energy Expenditure and Weight Loss: Results From a Systematic Review. Obesity, 2012. 20(11): p. 2307–2310.
92. Shen, W., et al., Effect of 2-year caloric restriction on organ and tissue size in nonobese 21- to 50-year-old adults in a randomized clinical trial: the CALERIE study. The American Journal of Clinical Nutrition, 2021. 114(4): p. 1295–1303.
93. Siervo, M., V. Boschi, and C. Falconi, Which REE prediction equation should we use in normal-weight, overweight and obese women? Clinical Nutrition, 2003. 22(2): p. 193–204.
94. Sivakumar, J., et al., Body Composition Changes Following a Very-Low-Calorie Pre-Operative Diet in Patients Undergoing Bariatric Surgery. Obesity surgery, 2020. 30(1): p. 119–126.
95. Speakman, J.R. and S.E. Mitchell, Caloric restriction. Molecular Aspects of Medicine, 2011. 32(3): p. 159–221.
96. St-Onge, M., et al., Impact of energy restriction with or without resistance training on energy metabolism in overweight and obese postmenopausal women: a Montreal Ottawa New Emerging Team group study. (1530-0374 (Electronic)).
97. Stec, K., et al., Effects of Fasting on the Physiological and Psychological Responses in Middle-Aged Men. Nutrients, 2023. 15(15): p. 3444.
98. Stubbs, R.J., et al., Potential effects of fat mass and fat-free mass on energy intake in different states of energy balance. European Journal of Clinical Nutrition, 2018. 72(5): p. 698–709.
99. Stubbs, R.J. and J. Turicchi, From famine to therapeutic weight loss: Hunger, psychological responses, and energy balance‐related behaviors. Obesity Reviews, 2021. 22(S2).
100. Sumithran, P., et al., Long-Term Persistence of Hormonal Adaptations to Weight Loss. New England Journal of Medicine, 2011. 365(17): p. 1597–1604.
101. Sylivris, A., et al., Body composition changes at 12 months following different surgical weight loss interventions in adults with obesity: A systematic review and meta‐analysis of randomized control trials. Obesity Reviews, 2022. 23(7): p. e13442.
102. Teutsch, H.F., Sex-specific regionality of liver metabolism during starvation; with special reference to the heterogeneity of the lobular periphery. Histochemistry, 1984. 81(1): p. 87–92.
103. Thillainadesan, S., et al., The impact of weight cycling on health outcomes in animal models: A systematic review and meta-analysis. Obesity Reviews, 2022. 23(5): p. e13416.
104. van Dale, D. and W.H. Saris, Repetitive weight loss and weight regain: effects on weight reduction, resting metabolic rate, and lipolytic activity before and after exercise and/or diet treatment. The American Journal of Clinical Nutrition, 1989. 49(3): p. 409–416.
105. Van Gemert, W., et al., Reduction of sleeping metabolic rate after vertical banded gastroplasty. International Journal of Obesity, 1998. 22(4): p. 343–348.
106. Veldhorst, M.A.B., M.S. Westerterp-Plantenga, and K.R. Westerterp, Gluconeogenesis and energy expenditure after a high-protein, carbohydrate-free diet12. The American Journal of Clinical Nutrition, 2009. 90(3): p. 519–526.
107. Villareal, D.T., et al., Bone Mineral Density Response to Caloric Restriction–Induced Weight Loss or Exercise-Induced Weight Loss: A Randomized Controlled Trial. Archives of Internal Medicine, 2006. 166(22): p. 2502–2510.
108. Viltart, O., P. Duriez, and V. Tolle, Metabolic and neuroendocrine adaptations to undernutrition in anorexia nervosa: from a clinical to a basic research point of view. 2018. 36(1).
109. Wang, A. and J.R. Speakman, Potential downsides of calorie restriction. Nature reviews. Endocrinology, 2025. 21(7): p. 427–440.
110. Wang, H., et al., The Impact of Weight Cycling on Health and Obesity. Metabolites, 2024. 14(6): p. 344.
111. Weigle, D.S., et al., Weight loss leads to a marked decrease in nonresting energy expenditure in ambulatory human subjects. Metabolism, 1988. 37(10): p. 930–936.
112. Weltan, S.M., et al., Influence of muscle glycogen content on metabolic regulation. American Journal of Physiology-Endocrinology and Metabolism, 1998. 274(1): p. E72–E82.
113. Westerterp, K.R., Metabolic adaptations to over—and underfeeding—still a matter of debate? European Journal of Clinical Nutrition, 2013. 67(5): p. 443–445.
114. Westerterp, K.R., et al., Energy intake, physical activity and body weight: a simulation model. British Journal of Nutrition, 1995. 73(3): p. 337–347.
115. Williams, R.L., et al., Effectiveness of weight loss interventions – is there a difference between men and women: a systematic review. Obesity Reviews, 2015. 16(2): p. 171–186.
116. Wilson, G.T., Relation of Dieting and Voluntary Weight Loss to Psychological Functioning and Binge Eating. Annals of Internal Medicine, 1993. 119(7_Part_2): p. 727–730.
117. Winter, T.A., et al., The Effect of Severe Undernutrition and Subsequent Refeeding on Whole-Body Metabolism and Protein Synthesis in Human Subjects. JPEN, Journal of Parenteral and Enteral Nutrition, 2005. 29(4): p. 221–8.
118. Wyatt, H.R., et al., Resting energy expenditure in reduced-obese subjects in the National Weight Control Registry2. The American Journal of Clinical Nutrition, 1999. 69(6): p. 1189–1193.
119. Yarizadeh, H., et al., Beneficial impact of exercise on bone mass in individuals under calorie restriction: a systematic review and Meta-analysis of randomized clinical trials. Critical Reviews in Food Science and Nutrition, 2021. 61(4): p. 553–565.
120. Zibellini, J., et al., Does Diet‐Induced Weight Loss Lead to Bone Loss in Overweight or Obese Adults? A Systematic Review and Meta‐Analysis of Clinical Trials. Journal of Bone and Mineral Research, 2015. 30(12): p. 2168–2178.
121. Fatty Acids and Lipotoxicity in Obesity and Diabetes. Novartis Foundation Symposia, 2007.
122. XBP1s regulates adiponectin multimerization in mice. Nature Reviews Endocrinology, 2014. 10(2): p. 66–66.
123. Abedelmalek, S., et al., Caloric Restriction Effect on Proinflammatory Cytokines, Growth Hormone, and Steroid Hormone Concentrations during Exercise in Judokas. Oxidative Medicine and Cellular Longevity, 2015. 2015: p. 1–8.
124. Ahmed, H., et al., Effect of food restriction on reproductive-related genes and reproductive hormones in adult female rats. European Review for Medical & Pharmacological Sciences, 2012. 16(12).
125. Alyar, G., F.Z. Umudum, and N. Akbaş, Changes in ghrelin, GLP-1, and PYY levels after diet and exercise in obese individuals. Revista da Associação Médica Brasileira, 2024. 70(1).
126. Anderson, K.C., et al., Endogenous Ghrelin Levels and Perception of Hunger: A Systematic Review and Meta-Analysis. Advances in Nutrition, 2023. 14(5): p. 1226–1236.
127. Arguin, H., et al., Short- and long-term effects of continuous versus intermittent restrictive diet approaches on body composition and the metabolic profile in overweight and obese postmenopausal women: a pilot study. Menopause (New York, N.Y.), 2012. 19(8): p. 870–876.
128. Arita, Y., et al., Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity. Biochemical and Biophysical Research Communications, 1999. 257(1): p. 79–83.
129. Arum, O., et al., Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging. F1000Research, 2015. 3: p. 256.
130. Athar, F., M. Karmani, and Nicole, Metabolic hormones are integral regulators of female reproductive health and function. Bioscience Reports, 2024. 44(1).
131. Atkinson, R.L. and D.L. Kaiser, Effects of calorie restriction and weight loss on glucose and insulin levels in obese humans. Journal of the American College of Nutrition, 1985. 4(4): p. 411–419.
132. Barzilai, N., et al., Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat. Journal of Clinical Investigation, 1998. 101(7): p. 1353–1361.
133. Benítez-Páez, A., et al., Sex, Food, and the Gut Microbiota: Disparate Response to Caloric Restriction Diet with Fiber Supplementation in Women and Men. Molecular Nutrition & Food Research, 2021. 65(8): p. 2000996.
134. Cangemi, R., et al., Long‐term effects of calorie restriction on serum sex‐hormone concentrations in men. Aging Cell, 2010. 9(2): p. 236–242.
135. Cangemi, R., et al., Long-term effects of calorie restriction on serum sex-hormone concentrations in men. Aging Cell, 2010. 9(2): p. 236–42.
136. Chawla, S., et al., The Window Matters: A Systematic Review of Time Restricted Eating Strategies in Relation to Cortisol and Melatonin Secretion. Nutrients, 2021. 13(8): p. 2525.
137. Choi, G.E., et al., FRI005 Appetite Response To Short-term Energy Restriction In Young Healthy Women. Journal of the Endocrine Society, 2023. 7(Supplement_1).
138. Cooper, J.A., Factors affecting circulating levels of peptide YY in humans: a comprehensive review. Nutrition Research Reviews, 2014. 27(1): p. 186–197.
139. Cooper, K.M. and K.E. Ackerman, Endocrine implications of relative energy deficiency in sport. Endocrinology of Physical Activity and Sport, 2020: p. 303–320.
140. Cumming, D.C., M.E. Quigley, and S.S.C. Yen, Acute suppression of circulating testosterone levels by cortisol in men. The journal of clinical endocrinology and metabolism, 1983. 57(3): p. 671–673.
141. Deblauw, J.A., et al., The effects of <scp>short‐term</scp> caloric restriction on cardiometabolic health in overweight/obese men and women: A single‐arm trial. Physiological Reports, 2023. 11(22).
142. Decuypere, E., et al., Effects of hyper-or hypothyroid status on growth, adiposity and levels of growth hormone, somatomedin C and thyroid metabolism in broiler chickens. Reproduction Nutrition Développement, 1987. 27(2B): p. 555–564.
143. Degoutte, F., et al., Food Restriction, Performance, Biochemical, Psychological, and Endocrine Changes in Judo Athletes. International journal of sports medicine, 2006. 27(1): p. 9–18.
144. Deighton, K., R.L. Batterham, and D.J. Stensel, Appetite and gut peptide responses to exercise and calorie restriction. The effect of modest energy deficits. Appetite, 2014. 81: p. 52–59.
145. Delhanty, P.J.D., S.J. Neggers, and A.J. van der Lely, MECHANISMS IN ENDOCRINOLOGY: Ghrelin: the differences between acyl- and des-acyl ghrelin. European Journal of Endocrinology, 2012. 167(5): p. 601–608.
146. Doucet, E., M. Pomerleau, and M.-E. Harper, Fasting and Postprandial Total Ghrelin Remain Unchanged after Short-Term Energy Restriction. The Journal of Clinical Endocrinology & Metabolism, 2004. 89(4): p. 1727–1732.
147. Douyon, L. and D.E. Schteingart, Effect of obesity and starvation on thyroid hormone, growth hormone, and cortisol secretion. Endocrinology and metabolism clinics of North America, 2002. 31(1): p. 173–189.
148. Dunaif, A., et al., Profound Peripheral Insulin Resistance, Independent of Obesity, in Polycystic Ovary Syndrome. Diabetes, 1989. 38(9): p. 1165–1174.
149. Dunn, J.P., et al., Caloric Restriction‐Induced Decreases in Dopamine Receptor Availability are Associated with Leptin Concentration. Obesity, 2017. 25(11): p. 1910–1915.
150. Elerian, A.E., et al., Efficacy of gender, anaerobic exercise and low calorie diet on leptin, ghrelin hormones and hunger perception: A comparative study. Obesity Medicine, 2020. 18: p. 100213.
151. Elliott-Sale, K.J., et al., Endocrine Effects of Relative Energy Deficiency in Sport. Int J Sport Nutr Exerc Metab, 2018. 28(4): p. 335–349.
152. Erta, G., et al., Impact of a 12-Week Dietary Intervention on Adipose Tissue Metabolic Markers in Overweight Women of Reproductive Age. International Journal of Molecular Sciences, 2024. 25(15): p. 8512.
153. Espelund, U., et al., Fasting Unmasks a Strong Inverse Association between Ghrelin and Cortisol in Serum: Studies in Obese and Normal-Weight Subjects. The Journal of Clinical Endocrinology & Metabolism, 2005. 90(2): p. 741–746.
154. Fantuzzi, G. and R. Faggioni, Leptin in the regulation of immunity, inflammation, and hematopoiesis. J Leukoc Biol, 2000. 68(4): p. 437–46.
155. Fenkci, V., et al., Decreased total antioxidant status and increased oxidative stress in women with polycystic ovary syndrome may contribute to the risk of cardiovascular disease. Fertility and Sterility, 2003. 80(1): p. 123–127.
156. Flanagan, E.W., et al., Calorie Restriction and Aging in Humans. Annual Review of Nutrition, 2020. 40(Volume 40, 2020): p. 105–133.
157. Fontana, A., et al., Reduction of leptin levels during acute exercise is dependent on fasting but not on caloric restriction during chronic exercise: A systematic review and meta-analysis. PLOS ONE, 2023. 18(11): p. e0288730.
158. Fontana, L., et al., Effect of Long-Term Calorie Restriction with Adequate Protein and Micronutrients on Thyroid Hormones. The Journal of Clinical Endocrinology & Metabolism, 2006. 91(8): p. 3232–3235.
159. Fontana, L., et al., Effects of 2‐year calorie restriction on circulating levels of IGF‐1, IGF‐binding proteins and cortisol in nonobese men and women: a randomized clinical trial. Aging Cell, 2016. 15(1): p. 22–27.
160. Fontana, R. and S.D. Torre The Deep Correlation between Energy Metabolism and Reproduction: A View on the Effects of Nutrition for Women Fertility. Nutrients, 2016. 8, DOI: 10.3390/nu8020087.
161. Frohnert, B.I. and D.A. Bernlohr, Protein carbonylation, mitochondrial dysfunction, and insulin resistance. Adv Nutr, 2013. 4(2): p. 157–63.
162. Gat-Yablonski, G., et al., Leptin reverses the inhibitory effect of caloric restriction on longitudinal growth. Endocrinology, 2004. 145(1): p. 343–50.
163. Ghachem, A., et al., Effects of a 6-month caloric restriction induced-weight loss program in obese postmenopausal women with and without the metabolic syndrome: a MONET study. Menopause, 2017. 24(8).
164. Hackney, A.C., Effects of endurance exercise on the reproductive system of men: the « exercise-hypogonadal male condition ». J Endocrinol Invest, 2008. 31(10): p. 932–8.
165. Hackney, A.C. and N.W. Constantini, Endocrinology of physical activity and sport. 2020: Springer.
166. Heiker, J.T., D. Kosel, and A.G. Beck-Sickinger, Molecular mechanisms of signal transduction via adiponectin and adiponectin receptors. Biological chemistry, 2010. 391(9): p. 1005–1018.
167. Hoffer, L.J., et al., Effects of Severe Dietary Restriction on Male Reproductive Hormones*. The Journal of Clinical Endocrinology & Metabolism, 1986. 62(2): p. 288–292.
168. Huda, M.S.B., J.P.H. Wilding, and J.H. Pinkney, Gut peptides and the regulation of appetite. Obesity reviews, 2006. 7(2): p. 163–182.
169. Huhmann, K., Menses Requires Energy: A Review of How Disordered Eating, Excessive Exercise, and High Stress Lead to Menstrual Irregularities. Clinical Therapeutics, 2020. 42(3): p. 401–407.
170. Ibrahim Abdalla, M.M., Ghrelin – Physiological Functions and Regulation. European Endocrinology, 2015. 11(2): p. 90.
171. Imbeault, P., et al., Unchanged fasting and postprandial adiponectin levels following a 4-day caloric restriction in young healthy men. Clinical Endocrinology, 2004. 60(4): p. 429–433.
172. Jiao, Z.-T. and Q. Luo, Molecular Mechanisms and Health Benefits of Ghrelin: A Narrative Review. Nutrients, 2022. 14(19): p. 4191.
173. Jin, Z., et al., Fasting appetite-related gut hormone responses after weight loss induced by calorie restriction, exercise, or both in people with overweight or obesity: a meta‐analysis. International Journal of Obesity, 2025.
174. Johansson, A., et al., The relative impact of chronic food restriction and acute food deprivation on plasma hormone levels and hypothalamic neuropeptide expression. Peptides (New York, N.Y. : 1980), 2008. 29(9): p. 1588–1595.
175. Kadowaki, T., Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. Journal of Clinical Investigation, 2006. 116(7): p. 1784–1792.
176. Kadowaki, T., et al., Adiponectin, Adiponectin Receptors, and Epigenetic Regulation of Adipogenesis. Cold Spring Harbor Symposia on Quantitative Biology, 2011. 76(0): p. 257–265.
177. Karra, E., K. Chandarana, and R.L. Batterham, The role of peptide YY in appetite regulation and obesity. The Journal of Physiology, 2009. 587(1): p. 19–25.
178. Kato, Y., et al., Regulation of Human Growth Hormone Secretion and Its Disorders. Internal Medicine, 2002. 41(1): p. 7–13.
179. Kaukua, J., et al., Sex Hormones and Sexual Function in Obese Men Losing Weight. Obesity Research, 2003. 11(6): p. 689–694.
180. Khalafi, M., M.E. Symonds, and A. Akbari, The impact of exercise training versus caloric restriction on inflammation markers: a systemic review and meta-analysis. Critical reviews in food science and nutrition, 2022. 62(15): p. 4226–4241.
181. Kim, S.-H. and M.-J. Park, Effects of growth hormone on glucose metabolism and insulin resistance in human. Annals of Pediatric Endocrinology & Metabolism, 2017. 22(3): p. 145–152.
182. Kojima, M. and K. Kangawa, Structure and Function of Ghrelin. Springer Berlin Heidelberg. p. 89–115.
183. Kolaczynski, J.W., et al., Responses of Leptin to Short-Term Fasting and Refeeding in Humans: A Link With Ketogenesis but Not Ketones Themselves. Diabetes, 1996. 45(11): p. 1511–1515.
184. Komatsu, T., et al., Mechanisms of calorie restriction: a review of genes required for the life-extending and tumor-inhibiting effects of calorie restriction. Nutrients, 2019. 11(12): p. 3068.
185. Korbonits, M., et al., Ghrelin—a hormone with multiple functions. Frontiers in Neuroendocrinology, 2004. 25(1): p. 27–68.
186. Koyama, K.I., et al., Changes in Acyl Ghrelin, Des-acyl Ghrelin, and Ratio of Acyl Ghrelin to Total Ghrelin with Short-term Refeeding in Female Inpatients with Restricting-type Anorexia Nervosa. Horm Metab Res, 2010. 42(08): p. 595–598.
187. Kraus, W.E., et al., 2 years of calorie restriction and cardiometabolic risk (CALERIE): exploratory outcomes of a multicentre, phase 2, randomised controlled trial. Lancet Diabetes Endocrinol, 2019. 7(9): p. 673–683.
188. La Russa, D., et al., Antioxidant/Anti-Inflammatory Effects of Caloric Restriction in an Aged and Obese Rat Model: The Role of Adiponectin. Biomedicines, 2020. 8(12): p. 532.
189. Lagisz, M., et al., Transgenerational effects of caloric restriction on appetite: a meta-analysis. Obesity Reviews, 2014. 15(4): p. 294–309.
190. Lambert, A.J. and B.J. Merry, Effect of caloric restriction on mitochondrial reactive oxygen species production and bioenergetics: reversal by insulin. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2004. 286(1): p. R71–R79.
191. Le Roux, C.W. and S.R. Bloom, Peptide YY, appetite and food intake. Proceedings of the Nutrition Society, 2005. 64(2): p. 213–216.
192. Lebrun, C.M., S.M. Joyce, and N.W. Constantini, Effects of Female Reproductive Hormones on Sports Performance. 2013, Humana Press. p. 281–322.
193. Lecoultre, V., E. Ravussin, and L.M. Redman, The Fall in Leptin Concentration Is a Major Determinant of the Metabolic Adaptation Induced by Caloric Restriction Independently of the Changes in Leptin Circadian Rhythms. The Journal of Clinical Endocrinology & Metabolism, 2011. 96(9): p. E1512–E1516.
194. Lee, S. and H.-B. Kwak, Effects of interventions on adiponectin and adiponectin receptors. Journal of Exercise Rehabilitation, 2014. 10(2): p. 60–68.
195. Levay, E.A., et al., Calorie restriction at increasing levels leads to augmented concentrations of corticosterone and decreasing concentrations of testosterone in rats. Nutrition research (New York, N.Y.), 2010. 30(5): p. 366–373.
196. Maglich, J.M., et al., The Nuclear Receptor CAR Is a Regulator of Thyroid Hormone Metabolism during Caloric Restriction. Journal of Biological Chemistry, 2004. 279(19): p. 19832–19838.
197. Mani, B.K. and J.M. Zigman, Ghrelin as a Survival Hormone. Trends in Endocrinology & Metabolism, 2017. 28(12): p. 843–854.
198. Manning, S. and R.L. Batterham, The Role of Gut Hormone Peptide YY in Energy and Glucose Homeostasis: Twelve Years On. Annual review of physiology, 2014. 76(1): p. 585–608.
199. Martin, B., et al., Caloric restriction: Impact upon pituitary function and reproduction. Ageing Research Reviews, 2008. 7(3): p. 209–224.
200. Martín, M., et al., Caloric Restriction Prevents Metabolic Dysfunction and the Changes in Hypothalamic Neuropeptides Associated with Obesity Independently of Dietary Fat Content in Rats. Nutrients, 2021. 13(7): p. 2128.
201. McGowan, B.M.C. and S.R. Bloom, Peptide YY and appetite control. Current opinion in pharmacology, 2004. 4(6): p. 583–588.
202. Meehan, C.A., et al., Mild Caloric Restriction Decreases Insulin Requirements in Patients With Type 2 Diabetes and Severe Insulin Resistance. Medicine, 2015. 94(30): p. e1160.
203. Melin, A., et al., Energy availability and the female athlete triad in elite endurance athletes. Scandinavian journal of medicine & science in sports, 2015. 25(5): p. 610–622.
204. Merali, C., et al., Sustained caloric restriction potentiates insulin action by activating prostacyclin synthase. Obesity, 2024. 32(12): p. 2286–2298.
205. Michael Conlon, J., The origin and evolution of peptide YY (PYY) and pancreatic polypeptide (PP). Peptides (New York, N.Y. : 1980), 2002. 23(2): p. 269–278.
206. Mitchell, S.E., et al., The effects of graded levels of calorie restriction: II. Impact of short term calorie and protein restriction on circulating hormone levels, glucose homeostasis and oxidative stress in male C57BL/6 mice. Oncotarget, 2015. 6(27): p. 23213.
207. Moller, N., et al., Growth hormone and protein metabolism. Clinical Nutrition, 2009. 28(6): p. 597–603.
208. Monda, V., et al., Short-Term Physiological Effects of a Very Low-Calorie Ketogenic Diet: Effects on Adiponectin Levels and Inflammatory States. International Journal of Molecular Sciences, 2020. 21(9): p. 3228.
209. Moreira-Andres, M.N., et al., THE EFFECT OF CALORIE RESTRICTION ON SERUM THYROID HORMONE BINDING PROTEINS AND FREE HORMONE IN OBESE PATIENTS. Clinical Endocrinology, 1980. 12(3): p. 249–255.
210. Murphy, C. and K. Koehler, Caloric restriction induces anabolic resistance to resistance exercise. European Journal of Applied Physiology, 2020. 120(5): p. 1155–1164.
211. Nakamura, Y., B.R. Walker, and T. Ikuta, Systematic review and meta-analysis reveals acutely elevated plasma cortisol following fasting but not less severe calorie restriction. Stress, 2016. 19(2): p. 151–157.
212. Nindl, B.C., et al., Altered secretion of growth hormone and luteinizing hormone after 84 h of sustained physical exertion superimposed on caloric and sleep restriction. Journal of Applied Physiology, 2006. 100(1): p. 120–128.
213. Nørrelund, H., et al., The Decisive Role of Free Fatty Acids for Protein Conservation during Fasting in Humans with and without Growth Hormone. The Journal of Clinical Endocrinology & Metabolism, 2003. 88(9): p. 4371–4378.
214. Olisah, M.C., et al., Effect of Starvation on Female Reproductive Hormones of Female Albino Rats. IPS Journal of Public Health, 2023. 3(1): p. 29–31.
215. Ondrak, K.S., Sex Differences in Energy Balance and Weight Control. Endocrinology of Physical Activity and Sport, 2020: p. 161–170.
216. Persaud, S.J. and G.A. Bewick, Peptide YY: more than just an appetite regulator. Diabetologia, 2014. 57(9): p. 1762–1769.
217. Polito, R., et al., The Role of Very Low Calorie Ketogenic Diet in Sympathetic Activation through Cortisol Secretion in Male Obese Population. Journal of Clinical Medicine, 2021. 10(18): p. 4230.
218. Rahmani, J., et al., The influence of fasting and energy restricting diets on IGF-1 levels in humans: A systematic review and meta-analysis. Ageing Research Reviews, 2019. 53: p. 100910.
219. Redman, L.M., et al., Effect of Caloric Restriction with and without Exercise on Metabolic Intermediates in Nonobese Men and Women. The Journal of Clinical Endocrinology & Metabolism, 2011. 96(2): p. E312–E321.
220. Redman, L.M., et al., The effect of caloric restriction interventions on growth hormone secretion in nonobese men and women. Aging Cell, 2010. 9(1): p. 32–39.
221. Remer, T. and L. Shi, LOW-CALORIE DIETING AND DIETERS’ CORTISOL LEVELS: DON’T FORGET CORTISONE. Biopsychosocial Science and Medicine, 2010. 72(6).
222. Rogozina, O.P., et al., Effect of Chronic and Intermittent Calorie Restriction on Serum Adiponectin and Leptin and Mammary Tumorigenesis. Cancer Prevention Research, 2011. 4(4): p. 568–581.
223. Sakharova, A.A., et al., Role of growth hormone in regulating lipolysis, proteolysis, and hepatic glucose production during fasting. J Clin Endocrinol Metab, 2008. 93(7): p. 2755–9.
224. Salehi-Abargouei, A., V. Izadi, and L. Azadbakht, The Effect of Low Calorie Diet on Adiponectin Concentration: A Systematic Review and Meta-Analysis. Hormone and metabolic research, 2015. 47(8): p. 549–555.
225. Saltiel, A.R. and C.R. Kahn, Insulin signalling and the regulation of glucose and lipid metabolism. Nature, 2001. 414(6865): p. 799–806.
226. Sato, T., et al., Structure, regulation and function of ghrelin. Journal of Biochemistry, 2012. 151(2): p. 119–128.
227. Schorr, M., et al., Cortisol Measures Across the Weight Spectrum. The Journal of Clinical Endocrinology & Metabolism, 2015. 100(9): p. 3313–3321.
228. Seidel, M., et al., A Systematic Review and Meta-Analysis Finds Increased Blood Levels of All Forms of Ghrelin in Both Restricting and Binge-Eating/Purging Subtypes of Anorexia Nervosa. Nutrients, 2021. 13(2): p. 709.
229. Shang, Y., et al., Dietary Modification for Reproductive Health in Women With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis. Frontiers in Endocrinology, 2021. 12.
230. Shekhar, S., et al., RF10 | PMON215 Greater changes in metabolic hormones are associated with a smaller decrease in pulsatile LH secretion in response to short term moderate energy restriction in healthy, young women. Journal of the Endocrine Society, 2022. 6(Supplement_1): p. A710–A711.
231. Shinmura, K., et al., Cardioprotective Effects of Short-Term Caloric Restriction Are Mediated by Adiponectin via Activation of AMP-Activated Protein Kinase. Circulation, 2007. 116(24): p. 2809–2817.
232. Silva, A.D. and S.R. Bloom, Gut Hormones and Appetite Control: A Focus on PYY and GLP-1 as Therapeutic Targets in Obesity. Gut and Liver, 2012. 6(1): p. 10–20.
233. Silva, J.E., The thermogenic effect of thyroid hormone and its clinical implications. Annals of internal medicine, 2003. 139(3): p. 205–213.
234. Smith, S.J., et al., Examining the effects of calorie restriction on testosterone concentrations in men: a systematic review and meta-analysis. Nutrition reviews, 2022. 80(5): p. 1222–1236.
235. Strauss, J.F., R.L. Barbieri, and S.S.C. Yen, Yen & Jaffe’s reproductive endocrinology : physiology, pathophysiology, and clinical management. Eighth edition. ed. Yen and Jaffe’s reproductive endocrinology. 2019, Philadelphia, PA: Elsevier.
236. Su, J., et al., Two ghrelin receptor agonists for adults with malnutrition: a systematic review and meta-analysis. Nutrition Journal, 2016. 15(1).
237. Suchacki, K.J., et al., The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent. bioRxiv, 2023: p. 2022.02.20.481222.
238. Sun, L.Y., et al., Growth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in mice. eLife, 2013. 2: p. e01098.
239. Svendsen, P.F., et al., The effect of a very low calorie diet on insulin sensitivity, beta cell function, insulin clearance, incretin hormone secretion, androgen levels and body composition in obese young women. Scandinavian journal of clinical and laboratory investigation, 2012. 72(5): p. 410–419.
240. Tam, C.S., et al., No Effect of Caloric Restriction on Salivary Cortisol Levels in Overweight Men and Women. Metabolism, 2014. 63(2): p. 194–198.
241. Theodorakis, N., et al., Beyond Calories: Individual Metabolic and Hormonal Adaptations Driving Variability in Weight Management—A State-of-the-Art Narrative Review. International Journal of Molecular Sciences, 2024. 25(24): p. 13438.
242. Tschöp, M., D.L. Smiley, and M.L. Heiman, Ghrelin induces adiposity in rodents. Nature, 2000. 407(6806): p. 908–913.
243. Ueno, H., et al., The role of PYY in feeding regulation. Regulatory peptides, 2008. 145(1): p. 12–16.
244. Varkaneh Kord, H., et al., The influence of fasting and energy-restricted diets on leptin and adiponectin levels in humans: A systematic review and meta-analysis. Clinical Nutrition, 2021. 40(4): p. 1811–1821.
245. Vijayakumar, A., et al., Biological effects of growth hormone on carbohydrate and lipid metabolism. Growth Hormone & IGF Research, 2010. 20(1): p. 1–7.
246. Vijayakumar, A., S. Yakar, and D. Leroith, The Intricate Role of Growth Hormone in Metabolism. Frontiers in Endocrinology, 2011. 2.
247. Wadden, T.A., et al., Short- and Long-Term Changes in Serum Leptin in Dieting Obese Women: Effects of Caloric Restriction and Weight Loss1. The Journal of Clinical Endocrinology & Metabolism, 1998. 83(1): p. 214–218.
248. Wang, Y., et al., Circulating acyl and des-acyl ghrelin levels in obese adults: a systematic review and meta-analysis. Scientific Reports, 2022. 12(1).
249. Wauters, M., R. Considine, and L. Van Gaal, Human leptin: from an adipocyte hormone to an endocrine mediator. European Journal of Endocrinology, 2000. 143(3): p. 293–311.
250. Wilsey, J. and P. Scarpace, Caloric restriction reverses the deficits in leptin receptor protein and leptin signaling capacity associated with diet-induced obesity: role of leptin in the regulation of hypothalamic long-form leptin receptor expression. Journal of Endocrinology, 2004. 181(2): p. 297–306.
251. Wondisford, F.E., Essentials of Endocrinology and Metabolism: A Practical Guide for Medical Students. 1 ed. 2020: Springer Cham. VIII, 299.
252. Wong, H.K., R. Hoermann, and M. Grossmann, Reversible male hypogonadotropic hypogonadism due to energy deficit. Clinical Endocrinology, 2019. 91(1): p. 3–9.
253. Wynne, K. and S.R. Bloom, The role of oxyntomodulin and peptide tyrosine–tyrosine (PYY) in appetite control. Nature clinical practice. Endocrinology & metabolism, 2006. 2(11): p. 612–620.
254. Yang, L., et al., Long-Term Calorie Restriction Enhances Cellular Quality-Control Processes in Human Skeletal Muscle. Cell Reports, 2016. 14(3): p. 422–428.
255. Zhu, J., et al., Short-term caloric restriction induced bone loss in both axial and appendicular bones by increasing adiponectin. Annals of the New York Academy of Sciences, 2020. 1474(1): p. 47–60.
256. Thompson, J., M.M. Manore, and J.S. Skinner, Resting metabolic rate and thermic effect of a meal in low-and adequate-energy intake male endurance athletes. International Journal of Sport Nutrition and Exercise Metabolism, 1993. 3(2): p. 194–206.
257. Cherif, A., et al., Effects of Intermittent Fasting, Caloric Restriction, and Ramadan Intermittent Fasting on Cognitive Performance at Rest and During Exercise in Adults. Sports medicine (Auckland), 2016. 46(1): p. 35–47.
258. Ein, N., B. Armstrong, and K. Vickers, The effect of a very low calorie diet on subjective depressive symptoms and anxiety: meta-analysis and systematic review. International Journal of Obesity, 2019. 43(7): p. 1444–1455.
259. Haynos, A.F., Experimental Analysis of a Brief Emotion Regulation Intervention for Dietary Restriction. 2015: University of Nevada, Reno.
260. Hofer, S.J., et al., The ups and downs of caloric restriction and fasting: from molecular effects to clinical application. EMBO Molecular Medicine, 2022. 14(1).
261. Kebbe, M., et al., Beyond weight loss: current perspectives on the impact of calorie restriction on healthspan and lifespan. Expert Review of Endocrinology & Metabolism, 2021. 16(3): p. 95–108.
262. Pankevich, D.E., et al., Caloric Restriction Experience Reprograms Stress and Orexigenic Pathways and Promotes Binge Eating. The Journal of Neuroscience, 2010. 30(48): p. 16399–16407.
263. Sujeta, A., Effects of short-term calorie restriction on cardiovascular autonomic response, mood status, cognition and motor performance. 2018, Lietuvos sporto universitetas.
264. Vitousek, K.M., et al., Caloric restriction for longevity: II—The systematic neglect of behavioural and psychological outcomes in animal research. European Eating Disorders Review, 2004. 12(6): p. 338–360.
265. Zhang, Y., et al., The effects of calorie restriction in depression and potential mechanisms. Current neuropharmacology, 2015. 13(4): p. 536–542.
266. Bosy-Westphal, A., et al., Effect of weight loss and regain on adipose tissue distribution, composition of lean mass and resting energy expenditure in young overweight and obese adults. International journal of obesity, 2013. 37(10): p. 1371–1377.
267. Bray, G.A. and C. Bouchard, The biology of human overfeeding: A systematic review. Obesity Reviews, 2020. 21(9): p. e13040.
268. Cioffi, I., et al., The incidence of the refeeding syndrome. A systematic review and meta-analyses of literature. Clinical Nutrition, 2021. 40(6): p. 3688–3701.
269. Drenick, E.J., I.F. Hunt, and M.E. Swendseid, Influence of Fasting and Refeeding on Body Composition. American Journal of Public Health and the Nations Health, 1968. 58(3): p. 477–484.
270. Dulloo, A.G., Physiology of weight regain: Lessons from the classic Minnesota Starvation Experiment on human body composition regulation. Obes Rev, 2021. 22 Suppl 2: p. e13189.
271. Dulloo, A.G., et al., The thrifty ‘catch-up fat’phenotype: its impact on insulin sensitivity during growth trajectories to obesity and metabolic syndrome. International journal of obesity, 2006. 30(4): p. S23–S35.
272. Ferro-Luzzi, A., et al., Basal metabolism of weight-stable chronically undernourished men and women: lack of metabolic adaptation and ethnic differences. The American journal of clinical nutrition, 1997. 66(5): p. 1086–1093.
273. Garber, A.K., et al., A systematic review of approaches to refeeding in patients with anorexia nervosa. International Journal of Eating Disorders, 2016. 49(3): p. 293–310.
274. Hall, K.D., Computational model of in vivo human energy metabolism during semistarvation and refeeding. American Journal of Physiology-Endocrinology and Metabolism, 2006. 291(1): p. E23–E37.
275. Lagerpusch, M., et al., Carbohydrate quality and quantity affect glucose and lipid metabolism during weight regain in healthy men. The Journal of nutrition, 2013. 143(10): p. 1593–1601.
276. Obarzanek, E., M.D. Lesem, and D.C. Jimerson, Resting metabolic rate of anorexia nervosa patients during weight gain. The American Journal of Clinical Nutrition, 1994. 60(5): p. 666–675.
277. Soares, M., et al., Energy supplementation reverses changes in the basal metabolic rates of chronically undernourished individuals. British journal of nutrition, 1992. 68(3): p. 593–602.
278. Winter, T.A., et al., The Effect of Severe Undernutrition and Subsequent Refeeding on Whole-Body Metabolism and Protein Synthesis in Human Subjects. Journal of Parenteral and Enteral Nutrition, 2005. 29(4): p. 221–228.
279. Zheng, P., et al., Risk factors for the development of refeeding syndrome in adults: A systematic review. Nutrition in Clinical Practice, 2025. 40(1): p. 76–92.
280. Fortes, L.S., et al., Effect of rapid weight loss on physical performance in judo athletes: is rapid weight loss a help for judokas with weight problems?*. International Journal of Performance Analysis in Sport, 2017. 17(5): p. 763–773.
281. Henning, P.C., B.-S. Park, and J.-S. Kim, Physiological Decrements During Sustained Military Operational Stress. Military Medicine, 2011. 176(9): p. 991–997.
282. Isacco, L., et al., Rapid weight loss influences the physical, psychological and biological responses during a simulated competition in national judo athletes. European Journal of Sport Science, 2020. 20(5): p. 580–591.
283. Koral, J. and F. and Dosseville, Combination of gradual and rapid weight loss: Effects on physical performance and psychological state of elite judo athletes. Journal of Sports Sciences, 2009. 27(2): p. 115–120.
284. Lakicevic, N., et al., Effects of Rapid Weight Loss on Judo Athletes: A Systematic Review. Nutrients, 2020. 12(5): p. 1220.
285. Lebron, M.A., J.R. Stout, and D.H. Fukuda, Physiological Perturbations in Combat Sports: Weight Cycling and Metabolic Function—A Narrative Review. Metabolites, 2024. 14(2): p. 83.
286. Martínez-Aranda, L.M., et al., Effects of Different Rapid Weight Loss Strategies and Percentages on Performance-Related Parameters in Combat Sports: An Updated Systematic Review. International Journal of Environmental Research and Public Health, 2023. 20(6): p. 5158.
287. Mendes, S.H., et al., Effect of rapid weight loss on performance in combat sport male athletes: does adaptation to chronic weight cycling play a role? British Journal of Sports Medicine, 2013. 47(18): p. 1155.
288. Motevalli, M.S., et al., The Effect of Rate of Weight Reduction on Serum Myostatin and Follistatin Concentrations in Competitive Wrestlers. International Journal of Sports Physiology and Performance, 2015. 10(2): p. 139–146.
289. Oxfeldt, M., et al., Low energy availability followed by optimal energy availability does not benefit performance in trained females. Med Sci Sports Exerc, 2024. 56: p. 902–16.
290. Roklicer, R., et al., The effects of rapid weight loss on skeletal muscle in judo athletes. Journal of Translational Medicine, 2020. 18(1).
291. Santos, D.F.C.D., W.-H. Yang, and E. Franchini, A scoping review of rapid weight loss in judo athletes: prevalence, magnitude, effects on performance, risks, and recommendations. Physical Activity and Nutrition, 2024. 28(3): p. 001–012.
292. Štangar, M., et al., Rapid weight loss among elite-level judo athletes: methods and nutrition in relation to competition performance. Journal of the International Society of Sports Nutrition, 2022. 19(1): p. 380–396.
293. Timpmann, S., et al., Acute effects of self-selected regimen of rapid body mass loss in combat sports athletes. J Sports Sci Med, 2008. 7(2): p. 210–7.
294. Yadollahzadeh, R., et al., The effects of rapid weight loss on aerobic and anaerobic power on athletes in weight-sensitive sports. Sport Science, 2015. 8(2): p. 30–34.
295. Crescenzo, R., et al., Skeletal muscle mitochondrial oxidative capacity and uncoupling protein 3 are differently influenced by semistarvation and refeeding. FEBS Letters, 2003. 544(1): p. 138–142.
296. Konrad, K.K., R.A. Carels, and D.M. Garner, Metabolic and psychological changes during refeeding in anorexia nervosa. Eat Weight Disord, 2007. 12(1): p. 20–6.
297. MUNCH, I.C., N.H. MARKUSSEN, and N.A. ÓRITSLAND, Resting oxygen consumption in rats during food restriction, starvation and refeeding. Acta Physiologica Scandinavica, 1993. 148(3): p. 335–340.
298. Salisbury, J.J., et al., Refeeding, metabolic rate, and weight gain in anorexia nervosa: a review. Int J Eat Disord, 1995. 17(4): p. 337–45.
299. Habib, S.S., et al., Circulating Adiponectin and Resistin Levels Are Associated with Adiposity Indices and Physical Fitness in Healthy Adult Males. Medical Science Monitor Basic Research, 2021. 27: p. e930322–1 – e930322–7.
300. Kmiec, Z., et al., Effects of Fasting and Refeeding on Serum Leptin, Adiponectin and Free Fatty Acid Concentrations in Young and Old Male Rats. Gerontology (Basel), 2005. 51(6): p. 357–362.
301. Colling, C., et al., Changes in serum cortisol levels after 10 days of overfeeding and fasting. American Journal of Physiology-Endocrinology and Metabolism, 2023. 324(6): p. E506–E513.
302. Dai, Z., et al., Effects of 10-Day Complete Fasting on Physiological Homeostasis, Nutrition and Health Markers in Male Adults. Nutrients, 2022. 14(18): p. 3860.
303. Haouari, M., et al., How Ramadan Fasting Affects Caloric Consumption, Body Weight, and Circadian Evolution of Cortisol Serum Levels in Young, Healthy Male Volunteers. Hormone and Metabolic Research, 2008. 40(08): p. 575–577.
304. Korbonits, M.R., et al., Metabolic and hormonal changes during the refeeding period of prolonged fasting. European Journal of Endocrinology, 2007. 157(2): p. 157–166.
305. Kassir, R., et al., Sleeve gastrectomy. A point of technique. International Journal of Surgery, 2014. 12(12): p. 1450–1451.
306. Lemarié, F., et al., Revisiting the metabolism and physiological functions of caprylic acid (C8:0) with special focus on ghrelin octanoylation. Biochimie, 2016. 120: p. 40–48.
307. Méquinion, M., Peripheral and central alterations in a chronic model of food restriction: role of ghrelin. 2014.
308. Ameredes, B.T., et al., Growth Hormone Improves Body Mass Recovery with Refeeding after Chronic Undernutrition-Induced Muscle Atrophy in Aging Male Rats. The Journal of Nutrition, 1999. 129(12): p. 2264–2270.
309. Crave, J.C., et al., Sex hormone-binding globulin (SHBG), insulin and insulin-like growth factor-I (IGF-I) in anorexia nervosa: effect of refeeding. Reproduction, nutrition, development, 1996. 36(4): p. 407–408.
310. Felig, P., E.B. Marliss, and G.F. Cahill, Metabolic response to human growth hormone during prolonged starvation. Journal of Clinical Investigation, 1971. 50(2): p. 411–421.
311. Hill, K., et al., Pilot Study of Growth Hormone Administration during the Refeeding of Malnourished Anorexia Nervosa Patients. Journal of child and adolescent psychopharmacology, 2000. 10(1): p. 3–8.
312. Ibrahim, B. and K. Briski, Deferred Feeding and Body Weight Responses to Short-Term Interruption of Fuel Acquisition: Impact of Estradiol. Hormone and Metabolic Research, 2014. 47(08): p. 611–621.
313. McCusker, R.H., et al., Effects of feeding, fasting and refeeding on growth hormone and insulin in obese pigs. Physiology & Behavior, 1985. 35(3): p. 383–388.
314. Nogueira, J.P., et al., Growth hormone level at admission and its evolution during refeeding are predictive of short-term outcome in restrictive anorexia nervosa. British Journal of Nutrition, 2013. 109(12): p. 2175–2181.
315. Prickett, T.C., et al., Response of plasma CNP forms to acute anabolic and catabolic interventions in growing lambs. Am J Physiol Endocrinol Metab, 2007. 292(5): p. E1395–400.
316. Quigley, K., et al., Effects of underfeeding and refeeding on GH and thyroid hormone secretion in young, middle-aged, and old rats. Experimental Gerontology, 1990. 25(5): p. 447–457.
317. Soeters, M.R., et al. Intermittent fasting differentially affects glucose , lipid and protein metabolism . 7. 2008.
318. Svanberg, E., et al., The Role of the Growth Hormone/Insulin-Like Growth Factor I Axis in Stimulation of Protein Synthesis in Skeletal Muscles Following Oral Refeeding. Endocrinology, 1998. 139(12): p. 4906–4910.
319. Wu, X.-Y., et al., Effects of starvation and refeeding on growth performance, appetite, growth hormone–insulin-like growth factor axis levels and digestive function of <i>Acipenser dabryanus</i>. British Journal of Nutrition, 2021. 126(5): p. 695–707.
320. Aamir, A.B., et al., Effects of intermittent fasting and caloric restriction on inflammatory biomarkers in individuals with obesity/overweight: A systematic review and meta-analysis of randomized controlled trials. Obesity Reviews, 2025. 26(1): p. e13838.
321. Al-Chalabi, S., Effect of Ramadan Fasting on Sex Hormones in Infertile Male. Tikrit Journal of Pharmaceutical Sciences, 2023. 9(2): p. 277–281.
322. Bosch De Basea, L., et al., Sex-Dependent Metabolic Effects in Diet-Induced Obese Rats following Intermittent Fasting Compared with Continuous Food Restriction. Nutrients, 2024. 16(7): p. 1009.
323. Cienfuegos, S., et al., Effect of Intermittent Fasting on Reproductive Hormone Levels in Females and Males: A Review of Human Trials. Nutrients, 2022. 14(11): p. 2343.
324. Comitato, R., et al., Sex Hormones and Macronutrient Metabolism. Critical Reviews in Food Science and Nutrition, 2015. 55(2): p. 227–241.
325. De Andrade, P.B.M., et al., Caloric restriction induces energy-sparing alterations in skeletal muscle contraction, fiber composition and local thyroid hormone metabolism that persist during catch-up fat upon refeeding. Frontiers in Physiology, 2015. 6.
326. De Souza, M.J., et al., Randomised controlled trial of the effects of increased energy intake on menstrual recovery in exercising women with menstrual disturbances: the ‘REFUEL’ study. Human Reproduction, 2021. 36(8): p. 2285–2297.
327. Dragano, N., E. Milbank, and M. López, Estradiol and appetite: To eat or not to eat. Mol Metab, 2020. 42: p. 101061.
328. Gabriel, S., et al., A Six-Week Follow-Up Study on the Sustained Effects of Prolonged Water-Only Fasting and Refeeding on Markers of Cardiometabolic Risk. Nutrients, 2022. 14(20): p. 4313.
329. Grinspoon, S., et al., Changes in regional fat redistribution and the effects of estrogen during spontaneous weight gain in women with anorexia nervosa123. The American Journal of Clinical Nutrition, 2001. 73(5): p. 865–869.
330. Horea, M., Refeeding in a rodent model of the female athlete triad. 2004, Texas Woman’s University: United States — Texas. p. 142.
331. Iwasa, T., et al., Effects of undernutrition and low energy availability on reproductive functions and their underlying neuroendocrine mechanisms. Endocrine Journal, 2022. 69(12): p. 1363–1372.
332. Kalam, F., et al., Effect of time‐restricted eating on sex hormone levels in premenopausal and postmenopausal females. Obesity (Silver Spring, Md.), 2023. 31(S1): p. 57–62.
333. Kalsekar, A.S., D.N. Abdelrahim, and M.E. Faris, Effect of calorie restriction and intermittent fasting on glucose homeostasis, lipid profile, inflammatory, and hormonal markers in patients with polycystic ovary syndrome: a systematic review. Frontiers in Nutrition, 2024. 11.
334. Komatsu, H., et al., Chronological Study on Changes in Luteinizing Hormone Release during Fasting and Refeeding in Ovariectomized Estrogen-primed Rats. Nihon Chikusan Gakkaiho, 2000. 71(3): p. 239–249.
335. Lin, S., et al., Effect of time restricted eating versus daily calorie restriction on sex hormones in males and females with obesity. 2024, Cold Spring Harbor Laboratory.
336. Loucks, A.B., M. Verdun, and E.M. Heath, Low energy availability, not stress of exercise, alters LH pulsatility in exercising women. Journal of applied physiology (1985), 1998. 84(1): p. 37–46.
337. Lucio-Oliveira, F. and C.R. Franci, Effect of the interaction between food state and the action of estrogen on oxytocinergic system activity. Journal of endocrinology, 2012. 212(2): p. 129.
338. Nagata, J.M., et al., Sex differences in refeeding among hospitalized adolescents and young adults with eating disorders. International Journal of Eating Disorders, 2022. 55(2): p. 247–253.
339. Rizzoto, G., et al., Calorie Restriction Modulates Reproductive Development and Energy Balance in Pre-Pubertal Male Rats. Nutrients, 2019. 11(9): p. 1993.
340. Schneider, J.E., Energy balance and reproduction. Physiology & Behavior, 2004. 81(2): p. 289–317.
341. Shakya, M. and K.P. Briski, Rebound Feeding in the Wake of Short-Term Suspension of Food Intake Differs in the Presence of Estrous Cycle Peak versus Nadir Levels of Estradiol. Endocrinology and Metabolism, 2017. 32(4): p. 475.
342. Shen, M. and H. Shi, Sex Hormones and Their Receptors Regulate Liver Energy Homeostasis. International Journal of Endocrinology, 2015. 2015: p. 1–12.
343. Tanabe, Y., T. Ogawa, and T. Nakamura, The effect of short-term starvation on pituitary and plasma LH, plasma estradiol and progesterone, and on pituitary response to LH-RH in the laying hen (Gallus domesticus). General and Comparative Endocrinology, 1981. 43(3): p. 392–398.
344. Tey, H., S. Lim, and A. Snodgrass, Refeeding oedema in anorexia nervosa. Singapore medical journal, 2005. 46(6): p. 308.
345. Valle, A., et al., Sex-related differences in energy balance in response to caloric restriction. American Journal of Physiology-Endocrinology and Metabolism, 2005. 289(1): p. E15–E22.
346. Wisse, B.E., et al., Effect of prolonged moderate and severe energy restriction and refeeding on plasma leptin concentrations in obese women*2. The American Journal of Clinical Nutrition, 1999. 70(3): p. 321–330.
347. Yang, X., et al., Intermittent Fasting in Female Reproduction: A Double-Edged Sword. Nutrition Reviews, 2025.
348. Yu, K., et al., 17β-estradiol promotes acute refeeding in hungry mice via membrane-initiated ERα signaling. Molecular Metabolism, 2020. 42: p. 101053.
349. Blackmore, D., Effect of Early Postnatal Starvation on Subsequent Thyroid Function. Neonatology (Basel, Switzerland), 1973. 23(5-6): p. 359–365.
350. Holness, M.J., et al., The relationship between fat synthesis and oxidation in the liver after re-feeding and its regulation by thyroid hormone. Biochemical Journal, 1987. 247(3): p. 621–626.
351. Karimi, R., et al., Adaptive Effects of Endocrine Hormones on Metabolism of Macronutrients during Fasting and Starvation: A Scoping Review. Metabolites, 2024. 14(6): p. 336.
352. Urrea, C.R., et al., Thyroid axis hormones and anthropometric recovery of children/adolescents with overweight/obesity: A scoping review. Frontiers in Nutrition, 2023. 9.
353. Allard, C., Les astrocytes et la détection hypothalamique du glucose: rôle métabolique et implication des connexines astrocytaires. 2012, Université de Bourgogne.
354. Bakkour, Z., Effets de l’insuffisance renale chronique experimentale (irc) sur la synthese et la degradation du glycogene hepatique: role de l’apport glucidique (amidon ou saccharose). 1997, Paris 7.
355. Keim, N.L., J.S. Stern, and P.J. Havel, Relation between circulating leptin concentrations and appetite during a prolonged, moderate energy deficit in women. The American journal of clinical nutrition, 1998. 68(4): p. 794–801.
356. Scharf, E., et al., The Effects of Prolonged Water-Only Fasting and Refeeding on Markers of Cardiometabolic Risk. Nutrients, 2022. 14(6): p. 1183.
357. Meek, C.L., et al., Expected values for gastrointestinal and pancreatic hormone concentrations in healthy volunteers in the fasting and postprandial state. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2021. 58(2): p. 108–116.
358. Rigamonti, A.E., et al., Effect of somatostatin infusion on peptide YY secretion: studies in the acute and recovery phase of anorexia nervosa and in obesity. European journal of endocrinology, 2011. 165(3): p. 421–427.
359. Ravussin, E., et al., A 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity. The journals of gerontology. Series A, Biological sciences and medical sciences, 2015. 70(9): p. 1097–1104.
360. Rising, R., et al., Concomitant interindividual variation in body temperature and metabolic rate. American journal of physiology: endocrinology and metabolism, 1992. 263(4): p. E730–E734.
361. Rochon, J., et al., Design and Conduct of the CALERIE Study: Comprehensive Assessment of the Long-term Effects of Reducing Intake of Energy. The journals of gerontology. Series A, Biological sciences and medical sciences, 2011. 66A(1): p. 97–108.
362. Soare, A., et al., Long-term calorie restriction, but not endurance exercise, lowers core body temperature in humans. Aging, 2011. 3(4): p. 374–379.